The National Cancer Institute's (NCI's) Genomic Data Commons (GDC) is a data sharing platform that promotes precision medicine in oncology. It is not just a database or a tool; it is an expandable knowledge network supporting the import and standardization of genomic and clinical data from cancer research programs. The GDC contains NCI-generated data from some of the largest and most comprehensive cancer genomic datasets, including The Cancer Genome Atlas (TCGA) and Therapeutically Applicable Research to Generate Effective Therapies (TARGET). These datasets have been processed using a common set of bioinformatics pipelines, so that the data can be directly compared.
Resource Description
Resource Type
Data Repository
Specialization
Mixed Adult and Pediatric
Data Update Date
12/30/2024
Data Content Type
Clinical, Genomics/Omics, Xenograft
Resource Tools
Visualization Tools
YES
Analytic Tools
YES
Case Disease Diagnosis
Acute megakaryoblastic leukaemia (1); Acute monoblastic and monocytic leukemia (2); Acute myeloid leukemia with inv(3)(q21q26.2) or t(3;3)(q21;q26.2); RPN1-EVI1 (3); Acute myeloid leukemia with maturation (1); Acute myeloid leukemia with mutated CEBPA (10); Acute myeloid leukemia with mutated NPM1 (17); Acute myeloid leukemia with myelodysplasia-related changes (7); Acute myeloid leukemia with t(6;9)(p23;q34); DEK-NUP214 (4); Acute myeloid leukemia with t(8;21)(q22;q22); RUNX1-RUNX1T1 (9); Acute myeloid leukemia with t(9;11)(p22;q23); MLLT3-MLL (6) ...
Number of Cases
129
Case Sex
Female (69); Male (60)
Case Age At Diagnosis
0 to 4 years (6); 5 to 9 years (4); 10 to 14 years (8); 15 to 19 years (5); 20 to 24 years (22); 25 to 29 years (22); 30 to 34 years (32); 35 to 39 years (30)
Published In
Program
Case Disease Diagnosis
Adenocarcinoma (2); B-cell Lymphoma, NOS (2); Burkitt Lymphoma (158); Burkitt-like Lymphoma (14); Diffuse Large B-cell Lymphoma, NOS (12); Kaposi Sarcoma (1); Lymphoepithelial Carcinoma (1); Squamous Cell Carcinoma, Keratinizing (5); Squamous Cell Carcinoma, Nonkeratinizing (14); Tumor (2) ...
Number of Cases
212
Case Sex
Female (81); Male (131)
Case Age At Diagnosis
0 to 4 years (27); 5 to 9 years (80); 10 to 14 years (24); 15 to 19 years (16); 20 to 24 years (8); 25 to 29 years (21); 30 to 34 years (20); 35 to 39 years (16)
Published In
Program
Case Disease Diagnosis
Angiosarcoma (17); Ductal carcinoma in situ, NOS (1); Infiltrating duct and lobular carcinoma (3); Infiltrating duct carcinoma, NOS (46); Infiltrating lobular carcinoma, NOS (2); Not Reported (5)
Number of Cases
74
Case Sex
Female (72); Male (2)
Case Age At Diagnosis
20 to 24 years (1); 25 to 29 years (8); 30 to 34 years (27); 35 to 39 years (38)
Published In
Program
Case Disease Diagnosis
Adenocarcinoma, NOS (4); Endometrioid Adenocarcinoma, NOS (3); Glioblastoma (22); Infiltrating Duct Carcinoma, NOS (16); Infiltrating Lobular Carcinoma, NOS (1); Renal Cell Carcinoma, NOS (10); Squamous Cell Carcinoma, NOS (1)
Number of Cases
57
Case Sex
Female (34); Male (23)
Case Age At Diagnosis
20 to 24 years (2); 25 to 29 years (3); 30 to 34 years (17); 35 to 39 years (35)
Published In
Program
Case Disease Diagnosis
Acinar cell carcinoma (1); Acinar cell tumor (3); Adenocarcinoma, diffuse type (14); Adenocarcinoma, intestinal type (2); Adenocarcinoma, NOS (464); Adenoid cystic carcinoma (15); Adnexal carcinoma (2); Adrenal cortical carcinoma (13); Astrocytoma, NOS (84); Atypical carcinoid tumor (1) ...
Number of Cases
1,705
Case Sex
Female (684); Male (1,021)
Case Age At Diagnosis
15 to 19 years (22); 20 to 24 years (152); 25 to 29 years (290); 30 to 34 years (480); 35 to 39 years (761)
Published In
Program
Case Disease Diagnosis
Abdominal Fibromatosis (1); Adenocarcinoma (1); Alveolar Rhabdomyosarcoma (1); Atypical Carcinoid Tumor (1); Epithelioid Sarcoma (1); Ewing Sarcoma (2); Glioblastoma (1); Malignant Melanoma, NOS (3); Mixed Type Rhabdomyosarcoma (1); Mucinous Adenocarcinoma (1) ...
Number of Cases
19
Case Sex
Female (8); Male (11)
Case Age At Diagnosis
0 to 4 years (1); 5 to 9 years (2); 10 to 14 years (5); 15 to 19 years (3); 20 to 24 years (1); 25 to 29 years (1); 30 to 34 years (3); 35 to 39 years (3)
Published In
Program
Case Disease Diagnosis
Adenocarcinoma, NOS (10); Adrenal Cortical Carcinoma (1); Astrocytoma, Anaplastic (1); Carcinoma, NOS (2); Cholangiocarcinoma (4); Cystosarcoma Phyllodes, NOS (1); Endometrioid Adenocarcinoma, NOS (1); Epithelial Tumor, Malignant (1); Glioblastoma Multiforme (1); Inflammatory Carcinoma (1) ...
Number of Cases
64
Case Sex
Female (51); Male (13)
Case Age At Diagnosis
0 to 4 years (1); 5 to 9 years (1); 20 to 24 years (4); 25 to 29 years (7); 30 to 34 years (12); 35 to 39 years (39)
Published In
Program
Case Disease Diagnosis
Multiple myeloma (19)
Number of Cases
19
Case Sex
Female (7); Male (12)
Case Age At Diagnosis
25 to 29 years (1); 30 to 34 years (4); 35 to 39 years (14)
Published In
Program
Case Disease Diagnosis
Acute leukemia, NOS (8); Acute lymphoblastic leukemia, NOS (115); Blastic plasmacytoid dendritic cell neoplasm (1); Chronic lymphocytic leukemia (1); Common precursor B ALL (998); Leukemia, NOS (51); Lymphoid leukemia, NOS (1); Neoplasm, uncertain whether benign or malignant (1); Nephroblastoma, NOS (52); Osteosarcoma, NOS (1) ...
Number of Cases
1,559
Case Sex
Female (554); Male (700); Not Reported (305)
Case Age At Diagnosis
0 to 4 years (1,146); 5 to 9 years (373); 10 to 14 years (27); 15 to 19 years (11); 20 to 24 years (2)
Project
Case Disease Diagnosis
Diffuse large B-cell lymphoma, NOS (52)
Number of Cases
52
Case Sex
Female (15); Male (37)
Case Age At Diagnosis
0 to 4 years (9); 10 to 14 years (1); 15 to 19 years (3); 20 to 24 years (6); 25 to 29 years (6); 30 to 34 years (9); 35 to 39 years (18)
Published In
Program
Case Disease Diagnosis
Papillary adenocarcinoma, NOS (12)
Number of Cases
12
Case Sex
Female (7); Male (5)
Case Age At Diagnosis
15 to 19 years (1); 20 to 24 years (2); 25 to 29 years (5); 30 to 34 years (3); 35 to 39 years (1)
Published In
Project
Case Disease Diagnosis
Acute Lymphocytic Leukemia (1,163); Acute Myeloid Leukemia, NOS (2,158); Clear Cell Sarcoma of Kidney (13); Ganglioneuroblastoma (130); Malignant Rhabdoid Tumor (69); Neuroblastoma, NOS (989); Osteosarcoma, NOS (297); Precursor B-Cell Lymphoblastic Leukemia (552); Wilms Tumor (651); Not Reported (5)
Number of Cases
6,027
Case Sex
Female (2,739); Male (3,287); Unknown (1)
Case Age At Diagnosis
0 to 4 years (2,850); 5 to 9 years (1,068); 10 to 14 years (1,131); 15 to 19 years (858); 20 to 24 years (90); 25 to 29 years (21); 30 to 34 years (3); 35 to 39 years (6)
Published In
Program
Case Disease Diagnosis
Acute Myeloid Leukemia, NOS (38); Adenocarcinoma with Mixed Subtypes (1); Adenocarcinoma, Endocervical Type (8); Adenocarcinoma, Intestinal Type (1); Adenocarcinoma, NOS (21); Adenosquamous Carcinoma (2); Adrenal Cortical Carcinoma (31); Aggressive Fibromatosis (1); Amelanotic Melanoma (1); Astrocytoma, Anaplastic (54) ...
Number of Cases
1,235
Case Sex
Female (634); Male (601)
Case Age At Diagnosis
10 to 14 years (6); 15 to 19 years (43); 20 to 24 years (151); 25 to 29 years (228); 30 to 34 years (347); 35 to 39 years (460)
Published In
Program