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Clinical Proteomic Tumor Analysis Consortium (CPTAC)
GDC
Data Resource:  GDC
Point of Contact:  
Zhining Wang,  
Program

About This Dataset
The National Cancer Institute's Clinical Proteomic Tumor Analysis Consortium (CPTAC) is a national effort to accelerate the understanding of the molecular basis of cancer through the application of large-scale proteome and genome analysis, or proteogenomics. CPTAC is a comprehensive and coordinated effort to accelerate the understanding of the molecular basis of cancer through the application of robust, quantitative, proteomic technologies and workflows. The overarching goal of CPTAC is to improve our ability to diagnose, treat and prevent cancer. To achieve this goal, the NCI launched CPTAC to systematically identify proteins that derive from alterations in cancer genomes and related biological processes, and provide this data with accompanying assays and protocols to the public. CPTAC has provided the GDC with genomic data from a total of 1100+ cancer patients with diverse disease types.
Core Data Elements
Number of Cases
57
Case Sex
Female (34); Male (23)
Case Age At Diagnosis
20 to 24 years (2); 25 to 29 years (3); 30 to 34 years (17); 35 to 39 years (35)
Case Race
Asian (17); Black or African American (2); Other (6); White (31); Unknown (1)
Case Ethnicity
Hispanic or Latino (4); Not Hispanic or Latino (19); Not Reported (34)
Case Disease Diagnosis
Adenocarcinoma, NOS (4); Endometrioid Adenocarcinoma, NOS (3); Glioblastoma (22); Infiltrating Duct Carcinoma, NOS (16); Infiltrating Lobular Carcinoma, NOS (1); Renal Cell Carcinoma, NOS (10); Squamous Cell Carcinoma, NOS (1)
Case Tumor Site
Body of Pancreas (1); Brain, NOS (10); Breast, NOS (12); Corpus Uteri (2); Endometrium (1); Frontal Lobe (6); Head of Pancreas (3); Kidney, NOS (10); Lower Lobe, Lung (1); Lung, NOS (1); Occipital Lobe (3); Pancreas, NOS (1); Temporal Lobe (3); Tongue, NOS (1); Upper lobe, Lung (2)
Number of Samples
114
Sample Assay Method
Methylation Array (44); miRNA Sequencing (54); RNA Sequencing (57); scRNA sequencing (4); Targeted Sequencing (3); Whole Exome Sequencing (57); Whole Genome Sequencing (44)
Sample Is Normal
Yes (57); No (57)
Additional Data Elements
DBGAP STUDY IDENTIFIER
DATA REPOSITORY
Projects
CPTAC-2 (12); CPTAC-3 (45)
Published In
https://doi.org/10.1074/mcp.tir119.001673
Charts
Female (34); Male (23)
34Female