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Childhood Cancer Model Atlas
VPCC
Data Resource:  VPCC
Point of Contact:  
Ron Firestein, MD/PhD,  
Cell Line

About This Dataset
The Childhood Cancer Model Atlas (CCMA) is the largest collection of high-risk paediatric solid tumour cell lines in the world, and one of the most valuable resources available for childhood cancer scientists globally. It provides a collection of well annotated and characterised models of childhood cancer with associated functional genomics screens and includes a searchable data portal that can be accessed by scientists worldwide. Precise, detailed data like this help scientists to collaborate globally and drive clinical translation to help sick children.
Core Data Elements
Number of Cases
501
Case Sex
Not Reported (501)
Case Age At Diagnosis
Pediatric and Young Adult (<40 years) (501)
Case Race
Not Reported (501)
Case Ethnicity
Not Reported (501)
Case Disease Diagnosis
Adrenal carcinoma (mets) (1); Adrenocortical carcinoma (1); Anaplastic astrocytoma (17); Anaplastic embryonal rhabdomyosarcoma (1); Anaplastic ependymoma (3); Anaplastic medulloblastoma (1); Atypical teratoid rhabdoid tumour (ATRT) (29); Carcinoma (adult) (5); Cholangiocarcinoma (1); Chordoma (8); Choroid plexus carcinoma (2); Clear cell sarcoma (2); Desmoplastic small round cell tumour (2); Diffuse midline glioma (DMG) (96); Embryonal rhabdomyosarcoma (5); Embryonal tumour with multilayered rosettes (ETMR) (8); Ependymoma (19); Epitheloid Sarcoma (1); Ewing's sarcoma (19); Ganglioglioma (1); Ganglioneuroma (1); Germ cell tumour (1); Giant cell sarcoma (1); Glioblastoma (35); Glioblastoma (adult) (32); Glioma (2); Hepatoblastoma (2); High grade glioma (HGG) (56); Inflammatory myofibroblastic tumour (IMFT) (2); Malignant peripheral nerve sheath tumour (3); Malignant rhabdoid tumour (MRT) (6); Medulloblastoma (19); Muco-epidermoid carcinoma (1); Neuroblastoma (33); Neuroblastoma (CNS) (1); Neuroblastoma (PDX) (11); No malignancy (2); Oligodendroglioma (3); Osteosarcoma (28); Pilocytic astrocytoma (1); Pineoblastoma (2); Primitive neuroectodermal tumour (PNET) (1); Retinoblastoma (1); Rhabdomyosarcoma (20); Sarcoma (CNS) (3); Sarcoma, Non CNS (3); Sarcoma, NOS (4); Synovial sarcoma (1); Not Reported (4)
Case Tumor Site
Bone and soft tissue (76); Brain and central nervous system (266); Neuroendocrine (44); Not Reported (115)
Number of Samples
1,235
Sample Assay Method
CRISPR Screens (194); DNA Methylation (253); Drug Screens (238); Proteomics (232); RNA Sequencing (292); Whole Genome Sequencing (258)
Additional Data Elements
DATA REPOSITORY
Published In
https://doi.org/10.1016/j.ccell.2023.03.007
Charts
Not Reported (501)
501Not Reported