We are some of Victoria's leading research, academic and clinical organisations, working together to make things better for children and adolescents with cancer through world-class medical research and innovation. This work demands that we harness cutting-edge technology and methods. Together, the VPCC's researchers, doctors, and families of kids with cancer can deliver research with real-world impact, better medical care, and improved training for the researchers and clinicians of the future. The VPCC was made possible thanks to the tireless efforts of the Children's Cancer Foundation and funding from the Australian Government's Medical Research Future Fund (MRFF). Our partnership organisations are The Royal Children's Hospital (RCH), Monash Children's Hospital (MCH), Hudson Institute of Medical Research, Murdoch Children's Research Institute (MCRI), Monash University, University of Melbourne, Peter MacCallum Cancer Centre, Walter and Eliza Hall Institute of Medical Research (WEHI) and the Children's Cancer Foundation. Childhood cancer investigators from these organisations have joined forces to drive impactful and interdisciplinary research, improve medical care, and train the childhood cancer leaders of tomorrow. The VPCC partnerships span discovery research and clinical innovation programs; integrated biobanking, data management and bioinformatics platforms; and capacity building for training the next generation of researchers and clinicians, annual scientific symposia and educational events.