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PFAS Exposure and Risk of Cancer
PFAS Exposure and Risk of Cancer
Data Resource:
DCEG
Point of Contact:
Jonathan Hofmann, PhD, MPH
,
hofmannjn@mail.nih.gov
Project
About This Dataset
DCEG investigators in the Occupational and Environmental Epidemiology Branch (OEEB) have developed a portfolio of research aimed at identifying cancer-types associated with per- and polyfluoroalkyl substances (PFAS). These studies are innovative for their direct assessment of exposure using banked serum specimens as well as their evaluation of risks at varying exposure levels, from occupational exposure to those found in the general population or among military personnel. These investigations informed the most recent evaluation of the carcinogenicity of two PFAS by the International Agency for Research on Cancer (IARC) Monograph Program. Perfluorooctanoic acid (PFOA), the most well-studied PFAS, was first classified in 2014 as a possible human carcinogen, and in 2023, the working group upgraded PFOA to a human carcinogen. The working group classified perfluorooctanesulfonic acid (PFOS) for the first time in 2023 as a possible human carcinogen.
Core Data Elements
Additional Data Elements
DATA REPOSITORY
https://dceg.cancer.gov/research/what-we-study/pfas
