Therapeutically Applicable Research to Generate Effective Treatments
Point of Contact: Center for Cancer Genomics, NCICCGenomics@mail.nih.gov
Program
The Therapeutically Applicable Research to Generate Effective Treatments (TARGET) program applies a comprehensive genomic approach to determine molecular changes that drive childhood cancers. The goal of the program is to use data to guide the development of effective, less toxic therapies. TARGET is organized into a collaborative network of disease-specific project teams.
Resource Description
Resource Type
Program
Specialization
Pediatric
Data Update Date
04/25/2025
Data Content Type
Clinical, Genomics/Omics, Xenograft
Resource Tools
Visualization Tools
Analytic Tools
Data Access
Case Disease Diagnosis
Acute Lymphoblastic Leukemia, NOS (233)
Number of Cases
233
Case Sex
Female (76); Male (155); Not Reported (2)
Case Age At Diagnosis
0 to 4 years (59); 5 to 9 years (20); 10 to 14 years (75); 15 to 19 years (74); 20 to 24 years (3); Pediatric and Young Adult (<40 years) (2)
Published In
Project
Case Disease Diagnosis
Acute Leukemias of Ambiguous Lineage (115); Acute Lymphoblastic Leukemia, NOS (1,586)
Number of Cases
1,701
Case Sex
Female (614); Male (763); Not Reported (324)
Case Age At Diagnosis
0 to 4 years (561); 5 to 9 years (280); 10 to 14 years (328); 15 to 19 years (194); 20 to 24 years (12); 25 to 29 years (2); Pediatric and Young Adult (<40 years) (324)
Published In
Project
Case Disease Diagnosis
Acute Myeloid Leukemia, NOS (2,146)
Number of Cases
2,146
Case Sex
Female (1,022); Male (1,124)
Case Age At Diagnosis
0 to 4 years (657); 5 to 9 years (393); 10 to 14 years (547); 15 to 19 years (490); 20 to 24 years (49); 25 to 29 years (10)
Published In
Project
Case Disease Diagnosis
Clear Cell Sarcoma of the Kidney (13)
Number of Cases
13
Case Sex
Male (13)
Case Age At Diagnosis
0 to 4 years (13)
Published In
Project
Case Disease Diagnosis
Acute Lymphoblastic Leukemia, NOS (18); Acute Myeloid Leukemia, NOS (2); Anaplastic Ependymoma, Posterior Fossa (1); Anaplastic Large Cell Lymphoma (2); B-Cell Acute Lymphoblastic Leukemia, NOS (2); Burkitt Lymphoma (1); Ependymoma (3); Ewing Sarcoma (4); Glioblastoma (6); Medulloblastoma (4) ...
Number of Cases
95
Case Sex
Female (37); Male (43); Not Reported (15)
Case Age At Diagnosis
0 to 4 years (38); 5 to 9 years (12); 10 to 14 years (16); 15 to 19 years (16); 20 to 24 years (1); 25 to 29 years (3); 30 to 34 years (1); Pediatric and Young Adult (<40 years) (9)
Published In
Project
Case Disease Diagnosis
Ganglioneuroblastoma (130); Neuroblastoma, NOS (989)
Number of Cases
1,119
Case Sex
Female (481); Male (638)
Case Age At Diagnosis
0 to 4 years (992); 5 to 9 years (102); 10 to 14 years (18); 15 to 19 years (5); 20 to 24 years (2)
Published In
Project
Case Disease Diagnosis
Osteosarcoma (282)
Number of Cases
282
Case Sex
Female (122); Male (160)
Case Age At Diagnosis
0 to 4 years (3); 5 to 9 years (33); 10 to 14 years (103); 15 to 19 years (112); 20 to 24 years (17); 25 to 29 years (8); 30 to 34 years (2); 35 to 39 years (4)
Published In
Project
Case Disease Diagnosis
Rhabdoid Tumor (69)
Number of Cases
69
Case Sex
Female (33); Male (36)
Case Age At Diagnosis
0 to 4 years (66); 5 to 9 years (2); 10 to 14 years (1)
Published In
Project
Case Disease Diagnosis
Wilms Tumor (652)
Number of Cases
652
Case Sex
Female (360); Male (291); Unknown (1)
Case Age At Diagnosis
0 to 4 years (474); 5 to 9 years (160); 10 to 14 years (15); 15 to 19 years (3)
Published In
Project
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