The PDXNet Portal provides a way for researchers to learn about the PDX models, sequencing data (DNA and RNA), and PDX Minimum Information metadata tools generated by the network for public use. The National Cancer Institute (NCI) launched the PDX (patient-derived xenografts) Development and Trial Centers Research Network (PDXNet) in September 2017 to accelerate translational research that uses PDX models and sequencing data. The PDXNet includes six PDX Development and Trial Centers (PDTCs) and the PDX Data Commons and Coordinating Center (PDCCC). PDXNet also works closely with the NCI Patient-Derived Model Repository (PDMR) to ensure data are collected and provided in a standardized format