PDX Development and Trial Centers Research Network
Point of Contact: PDXNet Steering Committee, https://www.pdxnetwork.org/contact
Data Repository
The PDXNet Portal provides a way for researchers to learn about the PDX models, sequencing data (DNA and RNA), and PDX Minimum Information metadata tools generated by the network for public use. The NCI launched the PDX (patient-derived xenografts) Development and Trial Centers Research Network (PDXNet) in September 2017 to accelerate translational research that uses PDX models and sequencing data. The PDXNet includes six PDX Development and Trial Centers and the PDX Data Commons and Coordinating Center. The two PDTCs added in 2018 focus exclusively on developing PDXs from minority patients. PDXNet also works closely with the NCI Patient-Derived Model Repository to ensure data are collected and provided in a standardized format.
Resource Description
Resource Type
Data Repository
Specialization
Mixed Adult and Pediatric
Data Update Date
04/12/2024
Data Content Type
Clinical, Genomics/Omics, Imaging, Xenograft
Resource Tools
Visualization Tools
YES
Analytic Tools
YES
Data Access
Case Disease Diagnosis
Adenocarcinoma (10); Adrenocortical Carcinoma (1); Alveolar Soft Part Sarcoma (1); Colorectal Cancer (2); Ewing Sarcoma/Peripheral PNET (3); Female Reproductive System Cancer (1); Fibrosarcoma (1); Gastrointestinal Stromal Tumor (2); Invasive Breast Carcinoma (3); Islet Cell Tumors (1) ...
Number of Cases
49
Case Sex
Female (30); Male (19)
Case Age At Diagnosis
15 to 19 years (4); 20 to 24 years (3); 25 to 29 years (11); 30 to 34 years (7); 35 to 39 years (24)
Published In
Xenograft
Case Disease Diagnosis
Adenocarcinoma (15); Breast Cancer (1); Cholangiocarcinoma (1); Chondrosarcoma (1); Hodgkin Lymphoma (1); Invasive Breast Carcinoma (20); Malignant Peripheral Nerve Sheath Tumor (2); Melanoma (3); Non-Rhabdomyosarcoma Soft Tissue Sarcoma (1); Osteosarcoma (1) ...
Number of Cases
49
Case Sex
Female (36); Male (12); Not Reported (1)
Case Age At Diagnosis
20 to 24 years (3); 25 to 29 years (8); 30 to 34 years (14); 35 to 39 years (24)
Published In
Xenograft