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PDX Development and Trial Centers Research Network
PDXNet
2
  • https://pdxnet.shinyapps.io/portal/
    • Point of Contact:  PDXNet Steering Committee,  
  • pdx-net@jax.org
    • Data Repository

    The PDXNet Portal provides a way for researchers to learn about the PDX models, sequencing data (DNA and RNA), and PDX Minimum Information metadata tools generated by the network for public use. The National Cancer Institute (NCI) launched the PDX (patient-derived xenografts) Development and Trial Centers Research Network (PDXNet) in September 2017 to accelerate translational research that uses PDX models and sequencing data. The PDXNet includes six PDX Development and Trial Centers (PDTCs) and the PDX Data Commons and Coordinating Center (PDCCC). PDXNet also works closely with the NCI Patient-Derived Model Repository (PDMR) to ensure data are collected and provided in a standardized format
    Resource Description
    Resource Type
    Data Repository
    Specialization
    Mixed Adult and Pediatric

    Data Update Date
    04/21/2025
    Data Content Type

    Clinical, Genomics/Omics, Imaging, Xenograft
    Resource Tools
    Visualization Tools
    YES
    Analytic Tools
    YES
    Data Access


    datasets
    DATASET SUMMARIES (2)
    PDXNet Portal PDMR Data
    Case Disease Diagnosis
    Adenocarcinoma (16); Adenocarcinoma, NOS (1); Adrenocortical carcinoma (1); Alveolar rhabdomyosarcoma (2); Alveolar soft part sarcoma (1); Cervical cancer, NOS (1); Cholangiocar.- intra/extrahepatic (3); Colorectal cancer, NOS (2); Embryonal rhabdomyosarcoma (1); Ewing sarcoma/Peripheral PNET (2) ...

    Number of Cases
    85

    Case Sex
    Female (55); Male (30)

    Case Age At Diagnosis
    10 to 14 years (2); 15 to 19 years (5); 20 to 24 years (6); 25 to 29 years (13); 30 to 34 years (19); 35 to 39 years (40)

    Published In
  • https://doi.org/10.1093/narcan/zcac014
  • https://doi.org/10.1186/s12967-021-02936-w
    • Xenograft
    PDXNet Portal Model
    Case Disease Diagnosis
    Adenocarcinoma (15); Breast Cancer (1); Cholangiocarcinoma (1); Chondrosarcoma (1); Hodgkin Lymphoma (1); Invasive Breast Carcinoma (20); Malignant Peripheral Nerve Sheath Tumor (2); Melanoma (3); Non-Rhabdomyosarcoma Soft Tissue Sarcoma (1); Osteosarcoma (1) ...

    Number of Cases
    49

    Case Sex
    Female (36); Male (12); Not Reported (1)

    Case Age At Diagnosis
    20 to 24 years (3); 25 to 29 years (8); 30 to 34 years (14); 35 to 39 years (24)

    Published In
  • https://doi.org/10.1158/0008-5472.can-17-0582
  • https://doi.org/10.1093/narcan/zcac014
    • Xenograft