Kids First Data Resource
Kids First Data Resource
12
Point of Contact:  Allison Heath,  
  • heathap@email.chop.edu
  • Data Repository

    The goal of the Gabriella Miller Kids First Pediatric Research Program (Kids First) is to help researchers uncover new insights into the biology of childhood cancer and structural birth defects, including the discovery of shared genetic pathways between these disorders.
    Resource Description
    Resource Type
    Data Repository
    Specialization
    Pediatric

    Data Update Date
    07/01/2024
    Data Content Type

    Clinical, Genomics/Omics, Imaging
    Resource Tools
    Visualization Tools
    YES
    Analytic Tools
    YES

    datasets
    DATASET SUMMARIES (12)
    Case Disease Diagnosis
    Adenoma (33); Adult Brainstem Glioma (3); Adult Brainstem Mixed Glioma (11); Atypical Teratoid Rhabdoid Tumor (131); Cavernous Hemangioma (29); Central Neurocytoma (10); Chordoma (15); Choroid Plexus Carcinoma (34); Choroid Plexus Papilloma (70); Craniopharyngioma (167) ...

    Number of Cases
    6,574

    Case Sex
    Female (3,211); Male (3,298); Unknown (65)

    Case Age At Diagnosis
    0 to 4 years (1,532); 5 to 9 years (1,453); 10 to 14 years (1,403); 15 to 19 years (937); 25 to 29 years (221); 30 to 34 years (68); 35 to 39 years (35); Pediatric and Young Adult (<40 years) (925)

    Project
    Case Disease Diagnosis
    Atrial Heart Septal Defect (81); Atrioventricular Septal Defect (196); Complete Atrioventricular Canal (197); Congenital Heart Disease (26); Congenital Heart Malformation (202); Down Syndrome (1,337); Partial Atrioventricular Canal (47); Patent Ductus Arteriosus (202); Patent Foramen Ovale (227); Precursor B-Cell Acute Lymphoblastic Leukemia (530) ...

    Number of Cases
    2,423

    Case Sex
    Female (1,165); Male (1,257); Unknown (1)

    Case Age At Diagnosis
    0 to 4 years (1,684); 5 to 9 years (32); 10 to 14 years (29); 15 to 19 years (8); 20 to 24 years (4); 25 to 29 years (1); Pediatric and Young Adult (<40 years) (665)

    Published In
  • https://doi.org/10.1534/g3.117.300366
  • https://doi.org/10.1352/1944-7558-123.6.514
  • Project
    Case Disease Diagnosis
    Maffucci Syndrome (19); Ollier Disease (56)

    Number of Cases
    211

    Case Sex
    Female (113); Male (98)

    Case Age At Diagnosis
    0 to 4 years (27); 5 to 9 years (13); 10 to 14 years (4); 15 to 19 years (1); 20 to 24 years (1); Pediatric and Young Adult (<40 years) (165)

    Project
    Case Disease Diagnosis
    Ewing's Sarcoma (677); Other (817); Peripheral Primitive Neuroectodermal Tumor (1); Primitive Neuroectodermal Tumor (10); Rhabdomyosarcoma (1); Sarcoma (5); Soft Tissue Sarcoma (1)

    Number of Cases
    1,512

    Case Sex
    Female (719); Male (793)

    Case Age At Diagnosis
    0 to 4 years (33); 5 to 9 years (77); 10 to 14 years (155); 15 to 19 years (92); 20 to 24 years (17); 25 to 29 years (4); 30 to 34 years (2); 35 to 39 years (1); Pediatric and Young Adult (<40 years) (1,131)

    Project
    Case Disease Diagnosis
    Acute Lymphoblastic Leukemia (23); B-Cell Acute Lymphoblastic Leukemia (1); Breast Cancer (2); Hodgkins Lymphoma (28); Hodgkins Lymphoma, Lymphocytic Depletion (4); Kidney Cancer (2); Lung Cancer (3); Myelofibrosis (2); Non-Hodgkin Lymphoma (9); Other (109) ...

    Number of Cases
    185

    Case Sex
    Female (100); Male (85)

    Case Age At Diagnosis
    0 to 4 years (6); 5 to 9 years (4); 10 to 14 years (2); 15 to 19 years (13); 25 to 29 years (3); 30 to 34 years (5); 35 to 39 years (4); Pediatric and Young Adult (<40 years) (148)

    Project
    Case Disease Diagnosis
    Benign Neoplasm of Skin (146); Brain Cancer (104); Brain Neoplasm (93); Cancer of Cerebellum (71); Connective and Soft Tissue Neoplasm (61); Cryptorchidism (64); Lymphoid Leukemia (63); Melanocytic Nevus (82); Neurofibromatosis (70); Neurofibromatosis Type 1 (103) ...

    Number of Cases
    1,777

    Case Sex
    Female (868); Male (909)

    Case Age At Diagnosis
    0 to 4 years (799); 5 to 9 years (327); 10 to 14 years (247); 15 to 19 years (56); Pediatric and Young Adult (<40 years) (348)

    Project
    Case Disease Diagnosis
    Intracranial Germ Cell Tumors (356)

    Number of Cases
    356

    Case Sex
    Female (159); Male (197)

    Case Age At Diagnosis
    0 to 4 years (10); 5 to 9 years (22); 10 to 14 years (50); 15 to 19 years (39); Pediatric and Young Adult (<40 years) (235)

    Project
    Case Disease Diagnosis
    Acute Myeloid Leukemia (60)

    Number of Cases
    60

    Case Sex
    Female (19); Male (19); Not Reported (22)

    Case Age At Diagnosis
    0 to 4 years (11); 5 to 9 years (11); 10 to 14 years (12); 15 to 19 years (24); 20 to 24 years (2)

    Published In
    Project
    Case Disease Diagnosis
    Ganglioneuroma (4); Intermixed Schwannian Stroma-Rich Ganglioneuroblastoma (23); Neuroblastoma (451); Nodular Ganglioneuroblastoma (31); Other (1,172)

    Number of Cases
    1,681

    Case Sex
    Female (860); Male (821)

    Case Age At Diagnosis
    0 to 4 years (498); 5 to 9 years (11); Pediatric and Young Adult (<40 years) (1,172)

    Published In
    Project
    Case Disease Diagnosis
    Anaplastic Ependymoma (4); Ewing Sarcoma (12); Glioblastoma (5); Hepatoblastoma (7); Medulloblastoma (14); Mixed Germ Cell Tumor (7); Neoplasms (344); Neuroblastoma (26); Osteosarcoma (14); Other (245) ...

    Number of Cases
    718

    Case Sex
    Female (354); Male (364)

    Case Age At Diagnosis
    0 to 4 years (90); 5 to 9 years (67); 10 to 14 years (61); 15 to 19 years (29); Pediatric and Young Adult (<40 years) (471)

    Project
    Case Disease Diagnosis
    Osteosarcoma (129)

    Number of Cases
    129

    Case Sex
    Female (52); Male (76); Unknown (1)

    Case Age At Diagnosis
    Pediatric and Young Adult (<40 years) (129)

    Project
    Case Disease Diagnosis
    T-Cell Acute Lymphoblastic Leukemia (1,358)

    Number of Cases
    1,358

    Case Sex
    Female (356); Male (1,002)

    Case Age At Diagnosis
    0 to 4 years (268); 5 to 9 years (471); 10 to 14 years (357); 15 to 19 years (181); Pediatric and Young Adult (<40 years) (81)

    Project