The Central Brain Tumor Registry of the United States (CBTRUS) is a not-for-profit research corporation, recognized by the international research community as the premier resource for annual histology-specific statistical information for all primary brain and other CNS tumors in the United States. The CBTRUS analytic database has been developed by compiling data from central (state) cancer registries, the District of Columbia, and Puerto Rico that include information on both malignant and non-malignant primary brain and other CNS tumors.