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Aberrant Activation of Wound Healing Programs within the Metastatic Niche Facilitates Lung Colonization by Osteosarcoma Cells
dbGaP
Data Resource:  dbGaP
Point of Contact:  
Ryan D. Roberts,  
Project

About This Dataset
Lung metastasis is responsible for nearly all deaths caused by osteosarcoma, the most common pediatric bone tumor. How malignant bone cells coerce the lung microenvironment to support metastatic growth is unclear. This study delineates how osteosarcoma cells educate the lung microenvironment during metastatic progression.
Core Data Elements
Number of Cases
5
Case Sex
Female (1); Male (4)
Case Age At Diagnosis
10 to 14 years (3); Pediatric and Young Adult (<40 years) (2)
Case Race
Black or African American (1); White (2); Unknown (2)
Case Ethnicity
Not Reported (5)
Case Disease Diagnosis
Osteosarcoma (5)
Number of Samples
7
Sample Analyte Type
RNA (7)
Sample Anatomic Site
Lung (7)
Sample Is Normal
No (7)
Additional Data Elements
DBGAP STUDY IDENTIFIER
GEO STUDY IDENTIFIER
Grant Information
R01CA260178
Targeting cooperative mechanisms of metastatic colonization in osteosarcoma
Published In
https://doi.org/10.1101/2024.01.10.575008
Charts
Male (4); Female (1)
4Male