Modelling Multi-Dimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A report from the Center for Cancer Research
Data Resource: dbGaP
Point of Contact:
Javed Khan,
Project
About This Dataset
Core Data Elements
Number of Cases
83Case Sex
Female (27); Male (56)
Case Age At Diagnosis
0 to 4 years (7); 5 to 9 years (5); 10 to 14 years (9); 15 to 19 years (15); 20 to 24 years (3); Pediatric and Young Adult (<40 years) (43)
Case Race
Not Reported (83)
Case Ethnicity
Not Reported (83)
Case Disease Diagnosis
Desmoplastic Small Round Cell Tumor (); Ewing Sarcoma (); Neuroblastoma (); Neuroendocrine Tumors (); Rhabdoid Tumor (); Rhabdomyosarcoma (); Sarcoma (); Synovial Sarcoma (); Transitional Cell Carcinoma (); Wilms Tumor ()
Number of Samples
121Sample Assay Method
RNA Sequencing (73); SNP Array (66); Whole Exome Sequencing (73)
Sample Anatomic Site
Abdomen (3); Adrenal Gland (1); Adrenal, Brain (2); Bone Marrow (5); Breast (2); Diaphragm (1); Ilium (1); Kidney (1); Left Axillary Node (1); Left Back (1); Left Chest (2); Left Chest (1); Left Clavicle (1); Left Femur (1); Left Lung (4); Left Mediastinum (1); Left Shoulder (1); Liver (1); Lung (13); Lung, Brain (2); Lymph Node (2); Omentum (1); Pancreas (2); Parotid Lymph Node (1); Pericardium (1); Rib (1); Right Eye (1); Right Suprarenal Gland (1); Scalp (3); Thyroid (1); Tumor (2); Unknown (60)
Additional Data Elements
CLINICAL TRIAL IDENTIFIER
NCT01109394DBGAP STUDY IDENTIFIER
Grant Information
ZIABC010998 | Identification of Novel Mutations In Pediatric Cancers |
ZIABC011002 | Bioinformatics: Systems Biology of Pediatric Cancers |
Published In
https://doi.org/10.1371/journal.pgen.1004475;https://doi.org/10.1158/2159-8290.cd-13-0639;https://doi.org/10.1158/1078-0432.ccr-15-2717
Charts
Male (56); Female (27)