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The UC San Diego Chronic Lymphocytic Leukemia (CLL) Study
dbGaP
Data Resource:  dbGaP
Point of Contact:  
Thomas J. Kipps,  
Project

About This Dataset
The UC San Diego Chronic Lymphocytic Leukemia Study is designed to identify genetic, epigenetic, and transcriptional changes important for CLL. This data release consists of samples collected to 1) identify genomic changes associated with CLL progression using serially collected tumor samples; 2) characterize the transcriptional consequences of SF3B1 mutation through RNA-seq; and 3) characterize the expression profiles of ROR1+ vs. ROR1- tumors. The samples were collected from participants at the University of California, San Diego Moores Cancer Center and the data was generated at UC San Diego or in collaboration with the BC Cancer Agency Genome Sciences Centre.
Core Data Elements
Number of Cases
49
Case Sex
Female (12); Male (37)
Case Age At Diagnosis
Pediatric and Young Adult (<40 years) (49)
Case Race
Not Reported (49)
Case Ethnicity
Not Reported (49)
Case Disease Diagnosis
Chronic Lymphocytic Leukemia (49)
Number of Samples
177
Sample Assay Method
Other (88); RNA Sequencing (87); Whole Exome Sequencing (2)
Sample Anatomic Site
Blood (157); Saliva (20)
Sample Is Normal
Yes (24); No (153)
Additional Data Elements
DBGAP STUDY IDENTIFIER
Grant Information
P01CA081534
Chronic Lymphocytic Leukemia Research Consortium
R21CA152613
Biomarkers of Disease Progression in CLL
Charts
Male (37); Female (12)
37Male