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Exome Sequencing of Pleuropulmonary Blastoma
dbGaP
Data Resource:  dbGaP
Point of Contact:  
Ashley Hill, MD,  
Project

About This Dataset
Pleuropulmonary blastoma (PPB) is a rare, aggressive pediatric cancer arising from the lung or pleural cavity. In this study, we sequenced and analyzed the exomes of 15 PPB matched tumor and normal pairs. This study is part of a larger effort to characterize pediatric cancers as part of the Slim Initiative for Genomic Medicine (SIGMA) project.
Core Data Elements
Number of Cases
15
Case Sex
Female (8); Male (7)
Case Age At Diagnosis
20 to 24 years (1); 25 to 29 years (1); 30 to 34 years (1); 35 to 39 years (4); Greater than 39 years (6); Not Reported (2)
Case Race
Not Reported (15)
Case Ethnicity
Not Reported (15)
Case Disease Diagnosis
Pleuropulmonary Blastoma (15)
Number of Samples
30
Sample Anatomic Site
Brain (1); Lung (29)
Sample Is Normal
Yes (15); No (15)
Additional Data Elements
DBGAP STUDY IDENTIFIER
Grant Information
R01CA143167
DICER1 and the Pleuropulmonary Blastoma Family Cancer Syndrome
R01HL109265
Mechanisms of Dicer1 Function in Lung Organogenesis and Cystic Lung Disease
R01HL111190
FGF9 Regulation of Lung Development and Pathogenesis of Pleuropulmonary Blastoma
Published In
https://doi.org/10.1038/onc.2014.150
Charts
Female (8); Male (7)
8Female