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Genomic Sequencing of Pediatric Rhabdoid Cancers
dbGaP
Data Resource:  dbGaP
Point of Contact:  
Charles Roberts, MD, PhD,  
Project

About This Dataset
In this study, we sequenced the exomes of 35 rhabdoid tumors, highly aggressive cancers of early childhood. This study is part of a larger effort to characterize pediatric cancers as part of the Slim Initiative for Genomic Medicine (SIGMA) project.
Core Data Elements
Number of Cases
35
Case Sex
Female (16); Male (19)
Case Age At Diagnosis
0 to 4 years (31); 5 to 9 years (2); Pediatric and Young Adult (<40 years) (2)
Case Race
Not Reported (35)
Case Ethnicity
Not Reported (35)
Case Disease Diagnosis
Rhabdoid Tumor (35)
Number of Samples
70
Sample Anatomic Site
Bladder (2); Blood (35); Brain (22); Kidney (4); Liver (1); Paraspinal (1); Retroperitoneal (1); Soft Tissue (2); Supraclavicular (1); Thoracic (1)
Sample Is Normal
Yes (35); No (35)
Additional Data Elements
DBGAP STUDY IDENTIFIER
Grant Information
R01CA046274
Genetics of pediatric rhabdoid tumors
R01CA113794
The function of Snf5 (SMARCB1), an epigenetic tumor suppressor
Published In
https://doi.org/10.1172/jci64400
Charts
Male (19); Female (16)
19Male