US Flag logoAn official website of the United States government
PDXNet Portal Model
PDXNet
Data Resource:  PDXNet
Point of Contact:  
PDXNet Steering Committee,  
Xenograft

About This Dataset
The PDXNet Portal Model summarizes verified model submissions to the Patient-Derived Models Repository made by the PDX Data and Trial Centers. Data are current to April 2025. This dataset consists of participants under the age of 40 years old.
Core Data Elements
Number of Cases
49
Case Sex
Female (36); Male (12); Not Reported (1)
Case Age At Diagnosis
20 to 24 years (3); 25 to 29 years (8); 30 to 34 years (14); 35 to 39 years (24)
Case Race
American Indian or Alaska Native (1); Asian (1); Black or African American (5); White (27); Not Reported (15)
Case Ethnicity
Hispanic or Latino (7); Not Hispanic or Latino (32); Not Reported (10)
Case Disease Diagnosis
Adenocarcinoma (15); Breast Cancer (1); Cholangiocarcinoma (1); Chondrosarcoma (1); Hodgkin Lymphoma (1); Invasive Breast Carcinoma (20); Malignant Peripheral Nerve Sheath Tumor (2); Melanoma (3); Non-Rhabdomyosarcoma Soft Tissue Sarcoma (1); Osteosarcoma (1); Papillary Thyroid Carcinoma (1); Rhabdomyosarcoma (2)
Case Tumor Site
Breast (21); Digestive/Gastrointestinal (15); Endocrine and Neuroendocrine (1); Gynecologic (1); Hematologic/Blood (1); Musculoskeletal (7); Skin (3)
Number of Samples
46
Sample Assay Method
RNA Sequencing (24); Whole Exome Sequencing (22)
Sample Is Xenograft
Yes (41); No (5)
Additional Data Elements
DATA REPOSITORY
Grant Information
U24CA224067
PDXNet Data Commons and Coordinating Center
U54CA224070
Rational Approaches to Melanoma Therapy
U54CA224076
PDX Trial Center for Breast Cancer Therapy
U54CA224083
Washington University PDX Development and Trial Center
U54CA283759
University of Pennsylvania Patient-derived Xenograft Development and Trials Center
U54CA283762
United for Health Equity - Living PDX Program (U4HELPP)
U54CA283766
University of California and UT Southwestern D-PDTC
Published In
https://doi.org/10.1158/0008-5472.can-17-0582;https://doi.org/10.1093/narcan/zcac014
Charts
Female (36); Male (12); Not Reported (1)
36Female