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Genes regulated in EML1 cells expressing the TEL-AML1 oncogene after 5 and 7 days of treatment with IL7 and FLT3 ligand
GEO
Data Resource:  GEO
Point of Contact:  
Myriam Alcalay,  
Project

About This Dataset
The t(12;21) translocation is the most common genetic rearrangement in childhood acute lymphoblastic leukemia (ALL) and gives rise to the TEL-AML1 fusion gene, which functions as a transcription factor. TEL-AML1 expression in EML1 cells results in an impairment of differentiation along the B-lymphoid lineage.
Core Data Elements
Case Sex
Not Reported ()
Case Age At Diagnosis
Pediatric and Young Adult (<40 years) ()
Case Race
Not Reported ()
Case Ethnicity
Not Reported ()
Case Disease Diagnosis
Acute Lymphoblastic Leukemia ()
Case Tumor Site
Blood ()
Additional Data Elements
GEO STUDY IDENTIFIER
Published In
https://doi.org/10.1038/onc.2015.50