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Gene expression profiling of children affected by acute lymphoblastic leukemia
GEO
Data Resource:  GEO
Point of Contact:  
Gerolamo Lanfranchi,  
Project

About This Dataset
We have examined gene expression profiling of 18 children with acute lymphoblastic leukemia (ALL). In particular, the ALL patients are subdivided in three different subtypes by morphological, immunophenotypic and cytogenetical parameters: 10 ALL-B, 5 ALL-T and 3 ALL-B with the specific chromosomal aberration MLL/AF4. We compared the transcription profiles of the leukemic samples by microarray competitive hybridization against an arbitrary total RNA reference prepared from normal human bone marrow. Two replicates of each experiment were done using different microarray slides, in which the sample and reference RNAs labeled either with Cy3 or Cy5 fluorochromes were crossed in both combinations.
Core Data Elements
Number of Cases
18
Case Sex
Not Reported (18)
Case Age At Diagnosis
Pediatric and Young Adult (<40 years) (18)
Case Race
Not Reported (18)
Case Ethnicity
Not Reported (18)
Case Disease Diagnosis
Acute Lymphoblastic Leukemia (18)
Case Tumor Site
Bone Marrow (18)
Additional Data Elements
GEO STUDY IDENTIFIER
Published In
https://pubmed.ncbi.nlm.nih.gov/15996926/
Charts
Not Reported (18)
18Not Reported