Childhood Cancer Data Initiative (CCDI): Comprehensive Genomic Sequencing of Pediatric Cancer Cases (CMRI/KUCC)
CCDI
Data Resource:  CCDI
Point of Contact:  
Roy Jensen, MD,  
Project

About This Dataset
Core Data Elements
Number of Cases
200
Case Sex
Female (89); Male (111)
Case Age At Diagnosis
0 to 4 years (92); 5 to 9 years (48); 10 to 14 years (38); 15 to 19 years (21); 20 to 24 years (1)
Case Race
Asian (1); Black or African American (10); Native Hawaiian or Other Pacific Islander (1); White (172); Unknown (16)
Case Ethnicity
Hispanic or Latino (27); Not Hispanic or Latino (157); Unknown (16)
Case Disease Diagnosis
Acute megakaryoblastic leukemia (1); Acute monocytic leukemia (1); Acute myeloid leukemia (megakaryoblastic) with t(1;22)(p13;q13); RBM15-MKL1 (1); Acute myeloid leukemia with abnormal marrow eosinophils (1); Acute myeloid leukemia with biallelic mutation of CEBPA (2); Acute myeloid leukemia with mutated NPM1 (2); Acute myeloid leukemia, 11q23 abnormalities (3); Acute myeloid leukemia, NOS (7); Acute myeloid leukemia, t(8;21)(q22;q22) (3); Adrenal cortical adenoma, NOS (1); Anaplastic large cell lymphoma, ALK positive (2); Atypical teratoid/rhabdoid tumor (3); B lymphoblastic leukemia/lymphoma with hyperdiploidy (6); B lymphoblastic leukemia/lymphoma with hypodiploidy (Hypodiploid ALL) (2); B lymphoblastic leukemia/lymphoma with t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1) (16); B lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3); E2A-PBX1 (TCF3-PBX1) (4); B lymphoblastic leukemia/lymphoma with t(9;22)(q34;q11.2); BCR-ABL1 (2); B lymphoblastic leukemia/lymphoma, BCR-ABL1-like (9); B lymphoblastic leukemia/lymphoma, NOS (35); Burkitt lymphoma, NOS (1); Central primitive neuroectodermal tumor (2); Chondroblastic osteosarcoma (1); Chronic myeloid leukemia, NOS (2); Clear cell meningioma (1); CNS embryonal tumor with rhabdoid features (1); Embryonal rhabdomyosarcoma, NOS (4); Ependymoma, anaplastic (1); Ewing sarcoma (3); Follicular lymphoma, NOS (1); Ganglioglioma, anaplastic (1); Ganglioneuroblastoma (1); Ganglioneuroma (1); Glioblastoma, NOS (1); Glioma, malignant (1); Hepatoblastoma, NOS (3); Hepatocellular carcinoma, fibrolamellar (1); Hodgkin lymphoma, NOS (1); Mediastinal large B-cell lymphoma (1); Medulloblastoma, non-WNT/non-SHH (6); Medulloblastoma, NOS (1); Medulloblastoma, SHH-activated and TP53-mutant (1); Medulloblastoma, WNT-activated, NOS (1); Mixed phenotype acute leukemia, B/myeloid, NOS (1); Mixed phenotype acute leukemia, T/myeloid, NOS (1); Myelodysplastic syndrome with multilineage dysplasia (1); Myelodysplastic syndrome with single lineage dysplasia (1); Myeloid leukemia associated with Down syndrome (1); Myxopapillary ependymoma (1); Nephroblastoma, NOS (10); Neuroblastoma, NOS (9); Osteosarcoma, NOS (1); Pilocytic astrocytoma (2); Precursor cell lymphoblastic leukemia, NOS (6); Renal cell carcinoma, NOS (1); Rhabdoid tumor, NOS (2); Rhabdomyosarcoma, NOS (2); Sarcoma, NOS (2); Sertoli-Leydig cell tumor of intermediate differentiation, NOS (1); T lymphoblastic leukemia/lymphoma (17); Therapy-related myeloid neoplasm (1); Yolk sac tumor, NOS (2)
Case Tumor Site
Adrenal Gland, NOS (11); Bones, Joints and Articular Cartilage Of Other and Unspecified Sites (3); Brain, NOS (22); Connective, Subcutaneous and Other Soft Tissues, NOS (10); Heart, Mediastinum, and Pleura (1); Hematopoietic and Reticuloendothelial Systems (132); Kidney, NOS (13); Liver And Intrahepatic Bile Ducts (4); Nasal Cavity and Middle Ear (1); Ovary (1); Spinal Cord, Cranial Nerves, and Other Parts of Central Nervous System (1); Testis, NOS (1)
Number of Samples
393
Sample Assay Method
ATAC Sequencing (25); RNA Sequencing (84); Whole Exome Sequencing (261); Whole Genome Sequencing (356)
Sample Is Normal
Yes (187); No (206)
Additional Data Elements
DBGAP STUDY IDENTIFIER
Grant Information
3P30CA168524-09S3
Cancer Center Support Grant
Charts
Male (111); Female (89)
111Male