Childhood Cancer Data Initiative (CCDI): OncoKids - NGS Panel for Pediatric Malignancies
CCDI
Data Resource:  CCDI
Point of Contact:  
Amie E. Hwang, PhD, MPH,  
Project

About This Dataset
Core Data Elements
Number of Cases
1,039
Case Sex
Female (448); Male (561); Not Reported (30)
Case Age At Diagnosis
0 to 4 years (338); 5 to 9 years (182); 10 to 14 years (219); 15 to 19 years (155); 20 to 24 years (14); 25 to 29 years (1); 30 to 34 years (1); 35 to 39 years (1); Pediatric and Young Adult (<40 years) (128)
Case Race
Asian (73); Black or African American (50); White (594); Not Reported (185); Unknown (137)
Case Ethnicity
Hispanic or Latino (483); Not Hispanic or Latino (362); Not Reported (57); Unknown (137)
Case Disease Diagnosis
Acinar cell carcinoma (1); Acute leukemia, NOS (90); Acute myeloid leukemia, NOS (44); Adenocarcinoma, NOS (1); Adenoid cystic carcinoma (1); Alveolar soft part sarcoma (2); Anaplastic large cell lymphoma, T-cell and Null-cell type (1); Astrocytoma, anaplastic, NOS (1); Astrocytoma, NOS (1); Atypical teratoid/rhabdoid tumor (4); B lymphoblastic leukemia/lymphoma with hyperdiploidy (143); B lymphoblastic leukemia/lymphoma, NOS (5); Burkitt lymphoma, NOS (5); Carcinoma, NOS (1); Chondroid chordoma (1); Chondrosarcoma, NOS (1); Choroid plexus carcinoma (10); Chronic myelogenous leukemia, BCR/ABL positive (8); Chronic myeloid leukemia, NOS (4); Clear cell sarcoma of kidney (2); CNS embryonal tumor, NOS (3); Composite Hodgkin and non-Hodgkin lymphoma (1); Craniopharyngioma, NOS (4); Cutaneous T-cell lymphoma, NOS (1); Diffuse large B-cell lymphoma, NOS (5); Diffuse midline glioma, H3 K27M-mutant (4); Embryonal rhabdomyosarcoma, NOS (35); Embryonal tumor with multilayered rosettes with C19MC alteration (1); Ependymoma, NOS (15); Epithelioid sarcoma, NOS (2); Ewing sarcoma (21); Ganglioglioma, anaplastic (1); Ganglioglioma, NOS (15); Glioblastoma, NOS (4); Glioma, malignant (20); Gliosarcoma (1); Hemangioma, NOS (6); Hepatoblastoma, NOS (14); Hodgkin lymphoma, nodular sclerosis, NOS (2); Hodgkin lymphoma, NOS (1); Juvenile myelomonocytic leukemia, NOS (3); Langerhans cell histiocytosis, disseminated (7); Leiomyosarcoma, NOS (1); Lentiginous melanocytic nevus (2); Leukemia, NOS (3); Liposarcoma, NOS (1); Lymphangioma, NOS (2); Lymphoid leukemia, NOS (2); Lymphoproliferative disorder, NOS (2); Malignant peripheral nerve sheath tumor, NOS (4); Medullary carcinoma, NOS (15); Medulloblastoma, NOS (30); Meningioma, NOS (4); Mixed germ cell tumor (5); Mixed phenotype acute leukemia, B/myeloid, NOS (3); Myelodysplastic syndrome, NOS (6); Myeloid leukemia, NOS (2); Myoepithelial carcinoma (4); Neoplasm, benign (21); Neoplasm, malignant (151); Neoplasm, metastatic (3); Neoplasm, uncertain whether benign or malignant (64); Nephroblastoma, NOS (26); Neuroblastoma, NOS (46); Neuroepithelioma, NOS (1); Nodular melanoma (2); Nuclear protein in testis (NUT)-associated carcinoma (1); Oligodendroglioma, anaplastic, NOS (1); Osteosarcoma, NOS (31); Papillary glioneuronal tumor (1); Papillary tumor of pineal region (1); Pilocytic astrocytoma (14); Pinealoma (1); Pineoblastoma (1); Pleomorphic xanthoastrocytoma, NOS (55); Pleuropulmonary blastoma (3); Precursor cell lymphoblastic lymphoma, NOS (5); Precursor T-cell lymphoblastic leukemia (1); Renal cell carcinoma, NOS (3); Retinoblastoma, NOS (1); Rhabdoid tumor, NOS (2); Sarcoma, NOS (7); Schwannoma, NOS (2); Sertoli-Leydig cell tumor, poorly differentiated (2); Squamous cell carcinoma, large cell, nonkeratinizing, NOS (1); Synovial sarcoma, spindle cell (5); Transient abnormal myelopoiesis (4); Transitional cell carcinoma, NOS (1); Yolk sac tumor, NOS (1); Unknown (3)
Case Tumor Site
Adrenal gland, NOS (25); Blood (309); Bone marrow (37); Bone, NOS (33); Brain, NOS (79); Connective, subcutaneous and other soft tissues, NOS (86); Eye, NOS (1); Female genital tract, NOS (2); Kidney, NOS (43); Liver (21); Lung, NOS (4); Lymph nodes of multiple regions (5); Major salivary gland, NOS (1); Meninges, NOS (5); Nasopharynx, NOS (1); Nervous system, NOS (174); Optic nerve (1); Ovary (3); Overlapping lesion of bones, joints and articular cartilage (34); Overlapping lesion of colon (1); Overlapping lesion of digestive system (1); Overlapping lesion of eye and adnexa (1); Overlapping lesion of heart, mediastinum and pleura (2); Overlapping lesion of lung (1); Overlapping lesion of respiratory system and intrathoracic organs (2); Overlapping lesion of retroperitoneum and peritoneum (1); Pineal gland (3); Retina (1); Skin, NOS (9); Spinal cord (3); Thyroid gland (18); Urinary system, NOS (1); Unknown (131)
Number of Samples
2,246
Sample Assay Method
AMPLICON (2,246)
Additional Data Elements
DBGAP STUDY IDENTIFIER
Grant Information
3P30CA014089-45S6
USC Norris Comprehensive Cancer Center (Core) Grant
Published In
https://doi.org/10.1016/j.jmoldx.2018.06.009
Charts
Male (561); Female (448); Not Reported (30)
561Male